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Modafinil and Sex - What You NEED to Know

Updated: Apr 3, 2022

Female taking a modafinil tablet

There has been a lot of discussion in recent years about the effects of Modafinil, a pharmaceutical substance recognized by many as a "smart drug".

Some people claim that it helps to improve cognitive function, and consider it as a nootropic

substance (by definition - a smart drug that possesses none to minimal side effects), others are a bit more skeptic.

Many people have speculated on the relations between Modafinil and Sex - how and if it affects things like libido, dating and intimate relations - this article will cover everything on this topic, so you'd know when it's best to abstain Modafinil, and when it can give you an edge.

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Modafinil Overview

For the uninformed about Modafinil, here's a quick recap on the important details:

Modafinil is a non-amphetamine wakefulness agent that was discovered in the late 1970s. It was approved by the FDA (foods and drugs administration) for narcolepsy in 1998, today it's also prescribed for patients with sleep-related medical conditions such as obstructive sleep apnea and shift-work-sleep-disorder.

The medical community and scientific literature see Modafinil as a wakefulness promoting drug (eugeroic), but plenty of users think of the compound as a stimulant, this is not true.

Modafinil does resemble the stimulant class of drugs because of its mechanism of action that targets the central nervous system (CNS), however it does that in a subtler fashion whilst also targeting CNS pathways such as the histaminergic and orexinergic, whom are not affected by amphetamines - at least not directly.

These systems and their neurotransmitters - Histamine and hypocretin, are modulating sleepiness, alertness, and wakefulness, Modafinil affinity towards these systems, enables patients with sleep related issues to function in life.

Since then, Modafinil has become one of the most popular "smart drugs" on the market, and it's being consumed by the masses - namely healthy individuals who seek the pharmaceutical drug to gain an edge in life and be more successful.

This has a name in the scientific community - cosmetic psychopharmacology - meaning healthy people who use drugs to enhance various cognitive traits to feel or perform better.

Modafinil is frequently utilized by students, entrepreneurs, and professionals to help with concentration, motivation, and focus.

Modafinil is not without its side effects, though. The most common ones are headaches and nausea. Less common but more serious side effects include anxiety, depression, and mania.

It's important to receive advice from your physician to see if there are any underlying risks for you, that might prevent you from using Modafinil.

With this mass adoption, the anecdotes and research about the correlations between Modafinil and sex have sprung like mushrooms after the rain.


Modafinil and Sex - What We Know

This segment will cover all we could've found about any risks associated with combining Modafinil and sex - aggregated from sources of anecdotal nature such as Reddit or our own experience, and the more formal information platforms like NCBI which consists of the scientific data.

What we know (a male's point of view):

Ambivalence about dates on Modafinil - a male member of our team once had a date on a 100 mg Modafinil tablet (1/2 of a full dose), he says:

I took Modafinil in the morning, needless to say that my checklist for the day was done in lightning speed. 10 hours post ingestion me and my date arrived to a fancy restaurant, I noticed pros and cons of being medicated while in this scenario. First, I'm verbal, I'm witty, it was great in that regard, full of confidence. I just felt in the zone you know, HD and tunnel vision. But that's shy of platitude because these phenomena are default with Modafinil for some. So the con was the fact that I was actually too chatty, and I came to realize that the morning after, when Modafinil was no longer playing around in my receptors, that this woman is surfing on a different "vibe" if you will, and that could've hindered rapport between us. So empathy and understanding of interlocutors around you, for me, is definitely deminshed.

What can we infer from this story?

First, take it with a grain of salt, your experience with Modafinil may be completely different.

We're all different organisms that react differently to pharmaceutical agents, you can't know for sure how it'll affect you on the social scene until you try.

Second, figure out how you handle social situations when you're on Moda before you jump to dates medicated on it - Modafinil might make you so work oriented or increase your anxiety that you're going to skip the date all together, we don't want that to happen now, do we?

Enhanced stamina - isn't that wonderful? Getting a solution for a major problem for many men, via a smart drug?

Because Modafinil reduces libido for men, it's likely you'll be able to go for extended periods of time in the bedroom, which may make your spouse happier and satisfied.

That is not advice for using Modafinil for that purpose, we recommend contacting an urologist for such matters.

Laser focus - who said improved cognition can only assist you at work? We beg to differ.

Modafinil seems to enhance sexual intercourse because suddenly you can be more mindful and aware of the hidden feedback of your partner; little peaks of pleasure, or contrary, signs of discomfort will float more easily to get your attention.

These dynamics, of understanding what pleases or displeases your partner in bed, are great for further development and deepening of any romantic or sexual relationship.

Pickup - Important note, this might be a hit or miss because for each individual there is a slightly different experience, thus your mileage may vary.

"Modafinil didn't quite make me a playboy, but credit is due since the first time I "picked up" a girl randomly and we went to her apartement to make sweet loving just a two hours later, was when I was on Armodafinil. It makes sense - this smart drug is known to inhibit fear via the Amygdala, so where I'd usually feel flustered to engage into conversation, I flourished. I guess the same logic applies for women - more coinfidence and less fear are two positive ingridents for getting the man you want."

Yet again, Modafinil is also known to cause anxiety, so it's important to assess how you react to the drug in that regard, before hitting the bars looking for a spouse or a one-night stand.

No all-nighters - unfortunately, since Modafinil inhibits men's sex drive, the prospect of going into a second round might not be achievable, but that's something the "audacious" of you should not worry about.

Safety - Modafinil or not, it's essential to use condoms or other forms of protection. And when a lot of dopamine is flowing through your brain, you might get side-tracked into thinking you can handle the situation without them. Delusions of grandeur in bed can be dangerous.


Is Modafinil Safe?

Most pharmacological cognitive enhancers entail side effects - the brain is a delicate construct, thus, any external forces that alter its chemical compositions will most likely bring unwanted effects along with the desired ones.

Luckily, Modafinil is considered relatively safe, and the most common side effects are mild:

  • Headaches

  • Anxiety

  • Nausea

  • Insomnia

  • Diarrhea

To combat these, the user should practice good lifestyle habits when consuming Modafinil, for instance:

  • Healthy diet consisting of vegetables, complex carbs, good fatty acids, anti-oxidants & inflammation foods.

  • 8-9 hours of adequate sleep.

  • Drink the recommended amount of water.

  • Reduce the intake - both dosage and frequency per week.

  • Doing any form of sport on a weekly basis.

However, the medical literature also stipulates what are the rare side effects Modafinil may induce, such as:

  • Chest pain

  • Rash

  • Shortness of breath

What's more, the studies have shown that this smart drug might harm the fetus, as such it is a pregnancy category C.

At this point we would like to point out - if you ingested Modafinil, or any supplement for that matter, and feel ill, get a medical assistance ASAP!

With that being said, Modafinil is considered a very safe smart drug, and it's reputation as one is even validated by the likes of the reputable scientific institutions of Harvard and Oxford.

In 2015, researches at these universities dubbed Modafinil as the "world's first safe smart drug", a key and historic moment in the art of transhumanism, indicating that a men-made substance could improve the human condition without severe downsides.

They elaborated that this smart drug is improving healthy individuals' cognitive metrics such as decision-making, focus, and problem-solving.

Studies about Modafinil and Sex are quite esoteric and few in numbers; we've already established what are our tips from personal experience, and the smart drug general safe profile - let's analyze the correlations with specific sexual conditions and Modafinil.

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Erectile Dysfunction

As we've outlined above, Modafinil might reduce the libido of the male user, this reduction in sexual desire might be too much for some and induce erectile dysfunction (ED).

ED (or impotence) is a medical condition where a male patient is unable to get or keep an erection.

The anecdotes on Reddit about Modafinil and sex shed some light on how ED is relevant in these dynamics.

One user posted a thread regarding writing about his studying session with an immense focus elicited by Modafinil, however he got concerned when he tried to pleasure himself, in the midsts of his studying:

"While I’m studying, I noticed that i cannot get it up. I got bored and started beating my thing and i can get an orgasm but the libido is not there. Suddenly, masturbation feels like a task and not a pleasure anymore."

Another, more elaborated Reddit anecdote, comes from a guy who has a routine of masturbating once a week to elevate testosterone levels, and Modafinil induced ED seemed to hinder his plans:

"To my surprise, I found it pretty difficult to get and hold an erection. I thought this was very unusual since I never have had problems getting hard"

However, this male also was in a fasting routine which might've put his body in a more conservative state, putting some bodily functions in a stagnation.

The scientific data about the correlation between Modafinil and ED is lacking, however it's important to note again - organisms are very complex orchestrations of biological processes.

This ambivalence in the stories quite distort the link between Modafinil and erectile dysfunction, for healthy male individuals if problems rise up (meaning your penis rises down), it is likely that it is a temporary situation because the drug possesses very minimal risks in general.


Modafinil and premature ejaculation

Premature ejaculation (PE) is a medial condition where a male partaking in sexual intercourse arrive to orgasm too fast, leaving their partner unsatisfied.

How does Modafinil affect these phenomena many men struggle with?

On the anecdotal level, there are myriads of reports of males finding it hard to finish when ingesting the drug, or other similar dopaminergic drugs with a mechanism of action (MOA) that resembles Modafinil's.

This Redditor, shared quite humorously his experience:

"Interesting, I have noticed a decreased libido with Moda so it would make sense that it keeps the little swimmers in the pool longer. It's very subtle however, and not as effective as thinking about baseball."

On the empirical level, this proof of concept study concluded that Modafinil mildly improved many sexual metrics of individuals suffering from PE.

55 patients, after 1 month of Modafinil supplementation, witnessed improvements in their intravaginal ejaculatory latency time (IELT).

Moreover, the subjective reports of the patients increased as indicated in the questionnaire:

  • Better control of ejaculation

  • More satisfaction from sex

  • Less introspective stress

  • Reduced interpersonal difficulty

"In an uncontrolled proof-of-concept study of men with treatment-naïve lifelong PE where IELT was self-reported without a stopwatch, modest improvements of both IELT and patient-reported outcome measures were observed. Future controlled clinical trials are necessary to confirm these findings."

With that being said, this is an uncontrolled study, hence it might've been skewed in some way or the other.

Couple in bed



Modafinil is a drug renowned for making its users workaholics filled with extreme motivation and great work ethic, not so much for increasing the need and want of having sex.

That's why we become inquisitive when we hear about the opposite sex of the spectrum - people whose lust is at its peak by ingesting Modafinil.

A non Modafinil using colleague of our team is a great example:

"I am a big believer in nootropics for accomplishment and fulfillment in life and specifically in work related frames, that's why I use nootropics formulas like mind lab pro, but Modafinil is just not the right fit for me - When I use Modafinil I usually enter my own bubble, all I could think of is sex, and until that happens (or masturbation) I'll be extremely irritated by default. I can't enjoy the cognitive enhancement of Modafinil because all I care about when I use it is reproducing, It is uncommon, but c'est la vie!

You probably noticed the discrepancy - Modafinil is a potent drug that can induce two completely opposite effects for different people, when it comes to hypersexuality the scientific literature has studies to shed light on the phenomena.

This study examines the case of a 35-year-old male diagnosed with bipolar disorder, ingesting an astronomical, supratherapeutic 1000 mg Modafinil dose:

"Hence, as neither any other drug used in the index case could be linked with such kind of behavior nor was there any switch to mania/hypomania/mixed episode which could explain such change in behavior, we concluded that the symptoms of hypersexual behavior was induced by modafinil"

Believe it or not, his Modafinil induced hypersexuality resulted in him masturbating 10-12 a day.

As part of its mechanism of action, Modafinil elevates dopamine (DA) levels by binding to DA receptors and altering the uptake of dopamine by its transporters in neurons and synapses.

Another fascinating case, of a 45-year-old female patient with idiopathic hypersomnia with no previous drug use who got prescribed with Modafinil to treat her daytime sleepiness, became very sexual after a period of 1 week of Modafinil treatment.

From 2-3 times a week, her mind pivoted towards sex every day, which was troublesome since her husband is 75 years old, making it impossible from him to keep up with her growing libido.

Again, the sexual desire was reduced after Modafinil dosage reduced from 100 mg/day to 50 mg/day.

That's essentially it, the scientific studies about Modafinil and hypersexuality are not infinite, it seems like a rare effect, but more research should be conducted.


Modafinil and Sex | Closing Thoughts

Without derogating all that have been written above, the only way for you to understand how Modafinil interacts with your sex life is by getting the first-hand experience.

If you want to consume the drug as a healthy individual seeking cognitive enhancement, beware of the possible positive or negative side effects, and remember that usually they are temporary as the dosage is decreased, or alternatively the frequency of use is decreased, it's all about safe and rational use of this smart drug.

If you have sexual related medical issues, it's best to contact your health care provider, or the sexologist, to gain better understandings of what interventions might be suitable for you.

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Important note: this article may contain affiliate links, with that being said, our articles are always made with good faith and intentions.

Please contact us if you find any outdated information in one of our guides or articles; we put a lot of time and effort into researching the medical studies, so the information presented is always scientific literature based from platforms such as NCBI.

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